Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 19/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 11/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23383939 | 1.00 | LPAR1 (0.45) | LPAR1LPAR3CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL23383994 | 0.94 | LPAR1 (0.41) | LPAR1LPAR3 | |
| SCHEMBL29948284 | 0.94 | LPAR1 (0.41) | LPAR1LPAR3 | |
| SCHEMBL23384394 | 0.92 | LPAR1 (0.44) | LPAR1LPAR3 | |
| SCHEMBL30073407 | 0.92 | LPAR1 (0.44) | LPAR1LPAR3 | |
| SCHEMBL23489634 | 0.90 | LPAR1 (0.38) | LPAR1LPAR3 | |
| SCHEMBL30482799 | 0.90 | LPAR1 (0.38) | LPAR1LPAR3 | |
| SCHEMBL25824396 | 0.90 | LPAR1 (0.41) | LPAR1LPAR3 | |
| SCHEMBL23384388 | 0.90 | LPAR1 (0.38) | LPAR1LPAR3 | |
| SCHEMBL30073434 | 0.90 | LPAR1 (0.40) | LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212149-A1 | TRIAZOLE CARBAMATE PYRIDYL SULFONAMIDES AS LPA RECEPTOR ANTAGONISTS AND USES THEREOF | GILEAD SCIENCES, INC. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212149-A1 | TRIAZOLE CARBAMATE PYRIDYL SULFONAMIDES AS LPA RECEPTOR ANTAGONISTS AND USES THEREOF | LPAR3, LPAR1, LPAR2 | LPAR1 2/4885LPAR3 1/4885CHRNB2 3209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.