Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 20/20 | 0.68 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | PLK1 | P53350 | 1/20 | 0.63 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.63 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.63 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25825199 | 0.90 | WEE1 (0.64) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL25819567 | 0.89 | WEE1 (0.65) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL21332682 | 0.84 | WEE1 (0.88) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL31613787 | 0.84 | WEE1 (0.88) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL21333282 | 0.84 | WEE1 (0.88) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL29482710 | 0.84 | WEE1 (0.88) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL21332681 | 0.84 | WEE1 (0.88) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL25825186 | 0.83 | WEE1 (0.45) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL25825206 | 0.83 | WEE1 (0.70) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL25825196 | 0.83 | WEE1 (0.80) | WEE1EGFRCYP3A4PLK1MAP3K19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |