Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 6/20 | 0.69 |
| ▸ | DNMT3A | Q9Y6K1 | 5/20 | 0.69 |
| ▸ | DNMT3L | Q9UJW3 | 2/20 | 0.69 |
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | MYC | P01106 | 1/20 | 0.54 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.54 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180467 | 0.95 | DNMT1 (0.74) | DNMT1DNMT3ADNMT3LMAPKAPK2USP2 | |
| SCHEMBL23999701 | 0.95 | DNMT1 (0.74) | DNMT1DNMT3ADNMT3LMAPKAPK2USP2 | |
| SCHEMBL25825393 | 0.89 | DNMT1 (0.72) | DNMT1DNMT3ADNMT3LMAPKAPK2USP2 | |
| SCHEMBL25821799 | 0.88 | DNMT1 (0.68) | DNMT1DNMT3ADNMT3LMAPKAPK2ALK | |
| SCHEMBL25825397 | 0.87 | DNMT1 (0.69) | DNMT1DNMT3ADNMT3LMAPKAPK2USP2 | |
| SCHEMBL13335891 | 0.87 | DNMT1 (0.69) | DNMT1DNMT3ADNMT3LMAPKAPK2USP2 | |
| SCHEMBL23999712 | 0.87 | DNMT1 (0.69) | DNMT1DNMT3ADNMT3LMAPKAPK2USP2 | |
| SCHEMBL13335885 | 0.87 | DNMT1 (0.76) | DNMT1DNMT3ADNMT3LMAPKAPK2USP2 | |
| SCHEMBL25826599 | 0.85 | DNMT1 (0.66) | DNMT1DNMT3ADNMT3LUSP2MAPT | |
| SCHEMBL25825404 | 0.85 | DNMT1 (0.66) | DNMT1DNMT3ADNMT3LMAPKAPK2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | DNMT1 4785/4885DNMT3A 4693/4885DNMT3L 4461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.