Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 8/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25729286 | 0.94 | KMT2A (0.47) | EPHX1KMT2AMEN1GLP1REPHX2 | |
| SCHEMBL22837784 | 0.88 | KMT2A (0.53) | KMT2AMEN1GLP1RLMNASMN1; SMN2 | |
| SCHEMBL21105906 | 0.88 | KMT2A (0.53) | KMT2AMEN1GLP1RLMNASMN1; SMN2 | |
| SCHEMBL22906472 | 0.84 | EPHX2 (0.48) | KMT2AMEN1GLP1REPHX2ALDH1A1 | |
| SCHEMBL23696006 | 0.83 | KMT2A (0.42) | KMT2AMEN1GLP1REPHX2CYP2C19 | |
| SCHEMBL22861655 | 0.83 | KMT2A (0.42) | KMT2AMEN1GLP1REPHX2CYP2C19 | |
| SCHEMBL22856377 | 0.83 | EPHX2 (0.46) | KMT2AMEN1GLP1REPHX2HPGD | |
| SCHEMBL22837679 | 0.82 | EPHX2 (0.45) | KMT2AMEN1GLP1REPHX2LMNA | |
| SCHEMBL23807144 | 0.82 | EPHX2 (0.42) | KMT2AMEN1GLP1REPHX2CYP2C19 | |
| SCHEMBL21105769 | 0.82 | EPHX2 (0.45) | KMT2AMEN1GLP1REPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219945-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219945-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | EPHX1 1684/4885KMT2A 445/4885MEN1 4055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.