Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 5/20 | 0.53 |
| ▸ | DNMT3A | Q9Y6K1 | 5/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.43 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | DNMT3L | Q9UJW3 | 3/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820634 | 0.95 | DNMT1 (0.57) | DNMT1DNMT3AKMT2AGAKRIPK2 | |
| SCHEMBL24003759 | 0.93 | DNMT1 (0.55) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL25826556 | 0.90 | DNMT1 (0.54) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL24006012 | 0.90 | DNMT1 (0.54) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL25487276 | 0.90 | DNMT1 (0.53) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL25487871 | 0.89 | DNMT1 (0.59) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL30290822 | 0.89 | DNMT1 (0.59) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL24003769 | 0.89 | DNMT1 (0.65) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL31395379 | 0.89 | DNMT1 (0.65) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL30287672 | 0.89 | DNMT1 (0.65) | DNMT1DNMT3AUSP2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | DNMT1 4335/4885DNMT3A 4603/4885USP2 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.