Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.51 |
| ▸ | CDK8 | P49336 | 1/20 | 0.51 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.48 |
| ▸ | ATR | Q13535 | 11/20 | 0.47 |
| ▸ | ATRIP | Q8WXE1 | 3/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.43 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25826718 | 0.88 | IP6K1 (0.45) | CCNCCDK8TBK1LRRK2MEN1 | |
| SCHEMBL25826717 | 0.88 | IP6K1 (0.48) | CCNCCDK8LRRK2MEN1KMT2A | |
| SCHEMBL24005893 | 0.87 | CCNC (0.55) | CCNCCDK8TGFBR1ACVR1MAPKAPK2 | |
| SCHEMBL24010995 | 0.83 | CCNC (0.54) | CCNCCDK8BMPR1BPDGFRBKIT | |
| SCHEMBL26317831 | 0.82 | CCNC (0.51) | CCNCCDK8BMPR1BPDGFRBKIT | |
| SCHEMBL25826722 | 0.82 | IRAK4 (0.43) | CCNCCDK8TBK1ATRACVR1 | |
| SCHEMBL25826715 | 0.81 | MAPT (0.52) | ATRLRRK2MEN1KMT2AKDM4E | |
| SCHEMBL25821244 | 0.80 | LRRK2 (0.43) | LRRK2 | |
| SCHEMBL25456835 | 0.79 | CCNC (0.50) | CCNCCDK8BMPR1BPDGFRBKIT | |
| SCHEMBL25820105 | 0.78 | CLK1 (0.44) | CCNCCDK8CLK1DYRK1ABMPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | CCNC 821/4885CDK8 567/4885TBK1 824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.