Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 17/20 | 0.68 |
| ▸ | MET | P08581 | 3/20 | 0.50 |
| ▸ | CCNC | P24863 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999699 | 0.92 | KDR (0.63) | KDRMETCCNCCDK8MAPKAPK2 | |
| SCHEMBL30210280 | 0.92 | KDR (0.63) | KDRMETCCNCCDK8MAPKAPK2 | |
| SCHEMBL30180360 | 0.92 | KDR (0.63) | KDRMETCCNCCDK8MAPKAPK2 | |
| SCHEMBL23999511 | 0.92 | KDR (0.63) | KDRMETCCNCCDK8MAPKAPK2 | |
| SCHEMBL25820956 | 0.87 | KDR (0.77) | KDRMETCCNCCDK8 | |
| SCHEMBL25826857 | 0.85 | KDR (0.58) | KDRCCNCCDK8MAPKAPK2 | |
| SCHEMBL18617616 | 0.85 | KDR (0.75) | KDRMET | |
| SCHEMBL23999470 | 0.85 | KDR (0.73) | KDRMET | |
| SCHEMBL24006212 | 0.85 | KDR (0.73) | KDRMET | |
| Hydrochloric Acid SCHEMBL18585949 | 0.84 | KDR (0.73) | KDRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | KDR 3271/4885MET 1336/4885CCNC 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.