Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31465653 | 0.85 | SSTR4 (0.34) | KAT6AKAT5PDK2L3MBTL1AAK1 | |
| SCHEMBL25426028 | 0.80 | — | — | |
| SCHEMBL25426032 | 0.80 | — | — | |
| SCHEMBL25427198 | 0.74 | MEN1 (0.37) | KAT6AKAT5PDK2L3MBTL1AAK1 | |
| SCHEMBL31440019 | 0.73 | KAT6A (0.43) | KAT6AKAT5PDK2L3MBTL1AAK1 | |
| SCHEMBL38664281 | 0.71 | PDK2 (0.39) | KAT6AKAT5PDK2AAK1HTR2C | |
| SCHEMBL25345280 | 0.70 | PDK2 (0.34) | KAT6AKAT5PDK2L3MBTL1AAK1 | |
| SCHEMBL29385268 | 0.69 | HTR2C (0.39) | AAK1GBA1HTR2CSLC6A4 | |
| SCHEMBL22276510 | 0.69 | PDK2 (0.40) | PDK2L3MBTL1AAK1GBA1 | |
| SCHEMBL22276649 | 0.69 | PDK2 (0.40) | PDK2L3MBTL1AAK1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133375-A1 | MACROCYCLIC COMPOUNDS AND USE AS KINASE INHIBITORS | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2023-07-13 | — | — | WO | disclosed |