Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3288412 | 0.98 | TDP1 (0.61) | TDP1MEN1GAAKMT2ACYP3A4 | |
| SCHEMBL23616304 | 0.98 | TDP1 (0.61) | TDP1MEN1GAAKMT2ACYP3A4 | |
| SCHEMBL6535307 | 0.98 | TDP1 (0.61) | TDP1MEN1GAAKMT2ACYP3A4 | |
| SCHEMBL9554443 | 0.95 | TDP1 (0.57) | TDP1MEN1GAAKMT2ACYP3A4 | |
| SCHEMBL28348827 | 0.94 | TDP1 (0.54) | TDP1MEN1GAAKMT2ACYP3A4 | |
| SCHEMBL904074 | 0.93 | TDP1 (0.66) | TDP1MEN1GAAKMT2ACYP3A4 | |
| SCHEMBL16061043 | 0.92 | MEN1 (0.53) | TDP1MEN1GAAKMT2ACYP3A4 | |
| SCHEMBL16487196 | 0.92 | TDP1 (0.69) | TDP1MEN1GAAKMT2ACYP3A4 | |
| SCHEMBL22276602 | 0.92 | TDP1 (0.69) | TDP1MEN1GAAKMT2ACYP3A4 | |
| SCHEMBL22276615 | 0.92 | TDP1 (0.69) | TDP1MEN1GAAKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125792-A1 | MULTI-SUBSTITUTED URACIL DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 杭州奥默医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |