Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 5/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24010185 | 0.94 | KDR (0.41) | GSK3BKDRABCG2KITTSHR | |
| SCHEMBL24010184 | 0.87 | KDR (0.49) | GSK3BKDRKITBRAF | |
| SCHEMBL24010272 | 0.86 | LRRK2 (0.38) | GSK3BKDRKITCSNK1A1CSNK1D | |
| SCHEMBL24006251 | 0.82 | KDR (0.46) | GSK3BKDRKITBRAF | |
| SCHEMBL24010187 | 0.79 | MAPKAPK2 (0.43) | KDRKITBRAF | |
| SCHEMBL24010188 | 0.77 | ABCG2 (0.41) | GSK3BKDRABCG2KITACP1 | |
| SCHEMBL23999402 | 0.74 | MAPKAPK2 (0.43) | GSK3BKDRABCG2CSNK1A1CSNK1D | |
| SCHEMBL23999403 | 0.73 | LRRK2 (0.43) | GSK3BKDRABCG2CSNK1A1CSNK1D | |
| SCHEMBL23999408 | 0.72 | MAPKAPK2 (0.49) | GSK3BKDRCSNK1A1CSNK1DCSNK1G2 | |
| SCHEMBL24006108 | 0.71 | KDR (0.58) | GSK3BKDRCSNK1A1CSNK1DCSNK1G2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | GSK3B 50/4885KDR 2851/4885ABCG2 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.