Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25730553 | 0.93 | S1PR1 (0.37) | S1PR1S1PR3S1PR5USP2CYP2D6 | |
| SCHEMBL26409616 | 0.92 | S1PR1 (0.38) | S1PR1S1PR3S1PR5CYP2D6CHRM3 | |
| SCHEMBL25924025 | 0.92 | USP2 (0.38) | S1PR1S1PR3S1PR5USP2CYP2D6 | |
| SCHEMBL25702619 | 0.91 | CYP2D6 (0.36) | S1PR1S1PR3S1PR5USP2CYP2D6 | |
| SCHEMBL23945863 | 0.89 | ACE2 (0.39) | S1PR1S1PR3S1PR5USP2CYP2D6 | |
| SCHEMBL23807293 | 0.87 | CYP2D6 (0.36) | S1PR1S1PR3S1PR5USP2CYP2D6 | |
| SCHEMBL23806518 | 0.87 | CYP2D6 (0.42) | CYP2D6CA1OPRM1OPRL1 | |
| SCHEMBL25833674 | 0.84 | CYP2D6 (0.36) | S1PR1S1PR3S1PR5USP2CYP2D6 | |
| SCHEMBL25480360 | 0.84 | USP2 (0.41) | S1PR1S1PR3S1PR5USP2CHRM3 | |
| SCHEMBL25654330 | 0.84 | S1PR1 (0.37) | S1PR1S1PR3S1PR5USP2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219945-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219945-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | S1PR1 2230/4885S1PR3 2064/4885S1PR5 2251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.