Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962937 | 0.85 | KMT2A (0.51) | KMT2AMEN1CA12CA9CA7 | |
| SCHEMBL21962922 | 0.84 | KMT2A (0.57) | KMT2AMEN1CA12CA9CA7 | |
| SCHEMBL7335528 | 0.84 | KMT2A (0.50) | KMT2AMEN1CA12CA9CA7 | |
| SCHEMBL7332197 | 0.84 | KMT2A (0.50) | KMT2AMEN1CA12CA9CA7 | |
| SCHEMBL7415092 | 0.82 | KMT2A (0.52) | KMT2AMEN1CA12CA9CA7 | |
| SCHEMBL7335530 | 0.82 | MEN1 (0.49) | KMT2AMEN1CA12CA9CA7 | |
| SCHEMBL22010526 | 0.81 | POLB (0.44) | KMT2AMEN1CA12CA9CA7 | |
| SCHEMBL7269972 | 0.81 | POLB (0.48) | KMT2AMEN1CA12CA9CA7 | |
| SCHEMBL25829683 | 0.79 | KMT2A (0.52) | KMT2AMEN1CA12CA9CA7 | |
| SCHEMBL25829682 | 0.79 | KMT2A (0.46) | KMT2AMEN1CA12CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3880666-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-06-28 | — | — | EP | disclosed |