Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25830558 | 0.92 | STING1 (0.68) | STING1TP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL25831112 | 0.85 | STING1 (0.63) | STING1TP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL25831445 | 0.85 | STING1 (0.69) | STING1TP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL25831175 | 0.85 | STING1 (0.65) | STING1TP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL25830402 | 0.84 | STING1 (0.79) | STING1TP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL25830766 | 0.81 | STING1 (0.63) | STING1TP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL25832053 | 0.81 | STING1 (0.84) | STING1TP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL21990159 | 0.80 | STING1 (0.93) | STING1TP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL25830940 | 0.79 | STING1 (0.49) | STING1TP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL20594650 | 0.79 | STING1 (1.00) | STING1TP53SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |