Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TRPC5 | Q9UL62 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TPH1 | P17752 | 2/20 | 0.34 |
| ▸ | TPH2 | Q8IWU9 | 2/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25830369 | 0.83 | SMN1; SMN2 (0.41) | KDM4ETRPC5LMNASMN1; SMN2TSHR | |
| SCHEMBL25300060 | 0.82 | ENPP1 (0.57) | ENPP1 | |
| SCHEMBL25830733 | 0.80 | KDM4E (0.33) | KDM4ELMNASMN1; SMN2HPGDTSHR | |
| SCHEMBL25830588 | 0.76 | ENPP1 (0.57) | ENPP1 | |
| SCHEMBL25826032 | 0.70 | ENPP1 (0.69) | ENPP1 | |
| SCHEMBL16931633 | 0.68 | MAPT (0.48) | SMN1; SMN2L3MBTL1HPGDTSHRALDH1A1 | |
| SCHEMBL25828075 | 0.67 | ENPP1 (0.42) | ENPP1 | |
| SCHEMBL25830410 | 0.66 | ENPP1 (0.61) | ENPP1 | |
| SCHEMBL25296598 | 0.66 | ENPP1 (0.56) | ENPP1 | |
| SCHEMBL16332074 | 0.65 | PIM1 (0.46) | KDM4EGFERLMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |