SCHEMBL25833151

SCHEMBL25833151

Cc1ccc(-c2noc(-c3ccc(OC/C(=C/F)CNC(=O)OC(C)(C)C)cc3)n2)cc1

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 16/20 0.53
HAVCR2 Q8TDQ0 3/20 0.47
NPC1 O15118 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21889023 0.93 AOC3 (0.63) AOC3HAVCR2
SCHEMBL21889037 0.90 AOC3 (0.63) AOC3RAB9A
SCHEMBL21889499 0.90 AOC3 (0.63) AOC3
SCHEMBL21889177 0.87 AOC3 (0.67) AOC3
SCHEMBL21889832 0.87 AOC3 (0.67) AOC3
SCHEMBL21889025 0.86 AOC3 (0.59) AOC3
SCHEMBL23329639 0.85 MAOB (0.46) AOC3NPC1MAPT
SCHEMBL21889026 0.84 AOC3 (0.74) AOC3
SCHEMBL21889824 0.84 AOC3 (0.65) AOC3
SCHEMBL21889527 0.84 AOC3 (0.74) AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3626699-B1 SSAO INHIBITOR SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2023-07-12 EP disclosed