Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.72 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21965448 | 1.00 | DDB1 (0.72) | DDB1CRBNGAATSHR | |
| SCHEMBL23551585 | 0.84 | DDB1 (0.68) | DDB1CRBNGAATSHR | |
| SCHEMBL26328184 | 0.84 | CRBN (0.52) | DDB1CRBN | |
| SCHEMBL23551582 | 0.84 | DDB1 (0.68) | DDB1CRBNGAATSHR | |
| SCHEMBL31554764 | 0.84 | CRBN (1.00) | DDB1CRBN | |
| SCHEMBL23551219 | 0.84 | DDB1 (0.72) | DDB1CRBN | |
| SCHEMBL23551584 | 0.84 | DDB1 (0.72) | DDB1CRBN | |
| SCHEMBL21965393 | 0.84 | DDB1 (1.00) | DDB1CRBN | |
| SCHEMBL21965374 | 0.84 | DDB1 (0.72) | DDB1CRBN | |
| SCHEMBL27241641 | 0.84 | CRBN (0.72) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125907-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |