Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.43 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
| ▸ | GABRE | P78334 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13253145 | 0.90 | PLA2G2C (0.43) | PLA2G2CANPEPENPEPFOLH1GNPAT | |
| SCHEMBL14090831 | 0.90 | PLA2G2C (0.43) | PLA2G2CANPEPENPEPFOLH1GNPAT | |
| SCHEMBL21335957 | 0.85 | PLA2G2C (0.47) | PLA2G2CANPEPENPEPFOLH1GNPAT | |
| SCHEMBL10936490 | 0.84 | CRAT (0.45) | PLA2G2CGNPATCRAT | |
| SCHEMBL4531941 | 0.83 | PLA2G2C (0.44) | PLA2G2CGNPATCRAT | |
| SCHEMBL1479318 | 0.83 | PLA2G2C (0.55) | PLA2G2CANPEPENPEPFOLH1RIMKLA | |
| SCHEMBL10947091 | 0.82 | PLA2G2C (0.50) | PLA2G2CANPEPENPEPFOLH1RIMKLA | |
| SCHEMBL3503915 | 0.82 | PLA2G2C (0.54) | PLA2G2CANPEPENPEPFOLH1RIMKLA | |
| SCHEMBL10947076 | 0.82 | PLA2G2C (0.50) | PLA2G2CANPEPENPEPFOLH1RIMKLA | |
| SCHEMBL6464991 | 0.80 | PLA2G2C (0.54) | PLA2G2CGNPATPLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209483-A1 | PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2023-07-12 | — | — | EP | disclosed |