Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 3/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746195 | 0.84 | PDE10A (0.49) | SCN10APDE10A | |
| SCHEMBL25303515 | 0.84 | SCN2A (0.55) | SCN2ATRPV1NPY5RSCN10ACCNB2 | |
| SCHEMBL5758675 | 0.83 | SCN2A (0.54) | SCN2ATRPV1NPY5RSCN10ACCNB2 | |
| Bromide SCHEMBL16210189 | 0.83 | SCN2A (0.54) | SCN2ATRPV1NPY5RSCN10ACCNB2 | |
| SCHEMBL19390585 | 0.81 | PDE10A (0.49) | SCN10APDE10A | |
| SCHEMBL27550011 | 0.80 | PDE10A (0.51) | NPY5RSCN10APDE10A | |
| SCHEMBL15586819 | 0.80 | SSTR3 (0.46) | SCN10ACCNB2CDK1CCNB1GSK3A | |
| SCHEMBL17215027 | 0.80 | PDE10A (0.49) | SCN10APDE10A | |
| SCHEMBL19390558 | 0.78 | SCN10A (0.60) | SCN2ANPY5RSCN10APDE10A | |
| SCHEMBL5756074 | 0.78 | SCN2A (0.49) | SCN2ATRPV1NPY5RSCN10ACCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135057-A1 | BICYCLIC TRIAZINE DERIVATIVES FOR THE TREATMENT OF CANCER | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2023-07-20 | — | — | WO | disclosed |