Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 4/20 | 0.63 |
| ▸ | ALK | Q9UM73 | 11/20 | 0.63 |
| ▸ | INSR | P06213 | 3/20 | 0.58 |
| ▸ | IGF1R | P08069 | 1/20 | 0.58 |
| ▸ | MET | P08581 | 3/20 | 0.56 |
| ▸ | CDK7 | P50613 | 2/20 | 0.54 |
| ▸ | CDK9 | P50750 | 2/20 | 0.54 |
| ▸ | NEK2 | P51955 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30266655 | 1.00 | AXL (0.63) | AXLALKINSRIGF1RMET | |
| SCHEMBL24073478 | 1.00 | AXL (0.63) | AXLALKINSRIGF1RMET | |
| SCHEMBL25834975 | 0.94 | AXL (0.60) | AXLALKINSRIGF1RMET | |
| SCHEMBL24073509 | 0.94 | AXL (0.60) | AXLALKINSRIGF1RMET | |
| SCHEMBL25835023 | 0.93 | AXL (0.59) | AXLALKINSRIGF1RMET | |
| SCHEMBL24073515 | 0.93 | AXL (0.59) | AXLALKINSRIGF1RMET | |
| SCHEMBL24073719 | 0.93 | ALK (0.65) | AXLALKINSRIGF1RMET | |
| SCHEMBL25834871 | 0.93 | ALK (0.65) | AXLALKINSRIGF1RMET | |
| SCHEMBL24073715 | 0.93 | AXL (0.63) | AXLALKINSRIGF1RMET | |
| SCHEMBL25834978 | 0.93 | AXL (0.63) | AXLALKINSRIGF1RMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227484-A1 | PYRIMIDINE COMPOUND AS AXL INHIBITOR | NANJING CHIA TAI TIANQING PHARMACEUTICAL CO., LTD. (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20230227484-A1 | PYRIMIDINE COMPOUND AS AXL INHIBITOR | NANJING CHIA TAI TIANQING PHARMACEUTICAL CO., LTD. (CN) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227484-A1 | PYRIMIDINE COMPOUND AS AXL INHIBITOR | AXL, FLT3, TYMP | AXL 1/4885ALK 87/4885INSR 1450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.