Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 7/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30356800 | 1.00 | GAA (0.47) | GAANAAADGAT1KDM4EKMT2A | |
| SCHEMBL17869153 | 0.86 | KDM4E (0.56) | NAAAKDM4EKMT2AEPHX2GRIN1 | |
| SCHEMBL21547716 | 0.86 | KDM4E (0.56) | NAAAKDM4EKMT2AEPHX2GRIN1 | |
| SCHEMBL17869155 | 0.86 | KDM4E (0.56) | NAAAKDM4EKMT2AEPHX2GRIN1 | |
| SCHEMBL21842101 | 0.81 | EPHX2 (0.47) | NAAADGAT1EPHX2GRIN1GRIN2B | |
| SCHEMBL21525523 | 0.81 | EPHX2 (0.47) | NAAADGAT1EPHX2GRIN1GRIN2B | |
| SCHEMBL17869600 | 0.81 | EPHX2 (0.47) | NAAADGAT1EPHX2GRIN1GRIN2B | |
| SCHEMBL17869601 | 0.81 | EPHX2 (0.47) | NAAADGAT1EPHX2GRIN1GRIN2B | |
| SCHEMBL32668750 | 0.81 | CYP2C19 (0.48) | GAADGAT1KDM4EKMT2AALDH1A1 | |
| SCHEMBL17869062 | 0.81 | CYP2C19 (0.48) | GAADGAT1KDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202990-A1 | CYCLOHEXYL SUBSTITUTED TRIAZOLES | HOFFMANN-LA ROCHE INC. (US) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202990-A1 | CYCLOHEXYL SUBSTITUTED TRIAZOLES | AVPR1A, AVPR1B, AVPR2 | GAA 4526/4885NAAA 3646/4885DGAT1 3441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.