Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 20/20 | 0.53 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25835837 | 0.92 | AVPR1A (0.57) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL25294684 | 0.91 | AVPR1A (0.62) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL25294683 | 0.91 | AVPR1A (0.62) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL25257458 | 0.91 | AVPR1A (0.61) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL25256320 | 0.91 | AVPR1A (0.61) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL25301504 | 0.89 | AVPR1A (0.53) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL25253428 | 0.89 | AVPR1A (0.57) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL25294596 | 0.89 | AVPR1A (0.64) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL25295312 | 0.89 | AVPR1A (0.57) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL25294597 | 0.89 | AVPR1A (0.64) | AVPR1AAVPR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202990-A1 | CYCLOHEXYL SUBSTITUTED TRIAZOLES | HOFFMANN-LA ROCHE INC. (US) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202990-A1 | CYCLOHEXYL SUBSTITUTED TRIAZOLES | AVPR1A, AVPR1B, AVPR2 | AVPR1A 1/4885AVPR2 3/4885KCNH2 2524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.