Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2972396 | 1.00 | KCNH2 (0.46) | KCNH2LIPGNR1H2NR1H3ESR1 | |
| SCHEMBL151723 | 1.00 | KCNH2 (0.46) | KCNH2LIPGNR1H2NR1H3ESR1 | |
| SCHEMBL258309 | 1.00 | KCNH2 (0.46) | KCNH2LIPGNR1H2NR1H3ESR1 | |
| SCHEMBL258323 | 1.00 | KCNH2 (0.46) | KCNH2LIPGNR1H2NR1H3ESR1 | |
| SCHEMBL258262 | 1.00 | KCNH2 (0.46) | KCNH2LIPGNR1H2NR1H3ESR1 | |
| SCHEMBL258329 | 1.00 | KCNH2 (0.46) | KCNH2LIPGNR1H2NR1H3ESR1 | |
| SCHEMBL258639 | 1.00 | KCNH2 (0.46) | KCNH2LIPGNR1H2NR1H3ESR1 | |
| SCHEMBL2971183 | 1.00 | KCNH2 (0.46) | KCNH2LIPGNR1H2NR1H3ESR1 | |
| SCHEMBL3673115 | 1.00 | KCNH2 (0.46) | KCNH2LIPGNR1H2NR1H3ESR1 | |
| SCHEMBL173701 | 1.00 | KCNH2 (0.46) | KCNH2LIPGNR1H2NR1H3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2586 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102478-A | Preparation method of 1, 4-dicarbonyl thiosemicarbazide compound and anti-infection application | 中国医学科学院药物研究所 | 2023-05-12 | — | — | CN | claimed |
| US-20220393118-A1 | TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF | CHE, CHI MING (CN) | 2022-12-08 | — | — | US | claimed |
| CN-115247000-A | Novel pigment and preparation method thereof | 上海百艳实业有限公司 | 2022-10-28 | — | — | CN | claimed |
| EP-4017936-A1 | TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF | Che, Chi Ming (HK) | 2022-06-29 | — | — | EP | claimed |
| CN-112142909-B | Resistance reducing agent and preparation method thereof | 中国石油天然气股份有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-107963982-B | Polyisocyanate composition and isocyanate polymer composition | 旭化成株式会社 | 2021-11-12 | — | — | CN | claimed |
| CN-105164238-B | Lubricating oil composition | 出光兴产株式会社 | 2021-06-29 | — | — | CN | claimed |
| WO-2021036978-A1 | TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF | CHE CHI MING (CN) | 2021-03-04 | — | — | WO | claimed |
| EP-3784677-A1 | NON-COORDINATING ANION TYPE ACTIVATORS CONTAINING CATION HAVING LARGE ALKYL GROUPS | ExxonMobil Chemical Patents Inc. (US) | 2021-03-03 | — | — | EP | claimed |
| CN-112409243-A | Tetradentate ligand, gold (III) complex, and preparation method and application thereof | 支志明 | 2021-02-26 | — | — | CN | claimed |
| US-6391936-B1 | ACRYLATE POLYURETHANE POLYMER | DSM N.V. (NL) | 2002-05-21 | — | — | US | claimed |
| EP-0589018-A1 | AMINES AS INHIBITORS OF SQUALENE SYNTHASE | ZENECA LIMITED (GB) | 1994-03-30 | — | — | EP | claimed |
| WO-1993020807-A1 | AMINES AS INHIBITORS OF SQUALENE SYNTHASE | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | claimed |
| US-5145591-A | Oil, nonseparating | NIPPON OIL CO., LTD. (JP) | 1992-09-08 | — | — | US | claimed |
| US-5015402-A | Catalytic formation of complexes of metal phosphorodithioates, as additives for lubricants and compounds for wear resistance | THE LUBRIZOL CORPORATION (US) | 1991-05-14 | — | — | US | claimed |
| CN-1038279-A | PYRAZOLOPYRIDINE TYPE MEVALONOLACTONES | NISSAN CHEMICAL IND LTD (JP) | 1989-12-27 | — | — | CN | claimed |
| WO-1989006237-A1 | BASIC METAL DIHYDROCARBYLPHOSPHORODITHIOATES | THE LUBRIZOL CORPORATION (US) | 1989-07-13 | — | — | WO | claimed |
| US-4638011-A | CARDIOVASCULAR DISORDERS, THROMBOLYTIC DISEASE | E. R. SQUIBB & SONS, INC. (US) | 1987-01-20 | — | — | US | claimed |
| US-4604471-A | PLASTIC STABILIZERS | BASF AKTIENGESELLSCHAFT (DE) | 1986-08-05 | — | — | US | claimed |
| EP-0159528-A1 | Tetrahydrofuranyl substituted prostaglandin analogs | E.R. Squibb & Sons, Inc. (US) | 1985-10-30 | — | — | EP | claimed |