Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.47 |
| ▸ | SAT1 | P21673 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856264 | 0.77 | — | — | |
| SCHEMBL17754006 | 0.75 | LPAR3 (0.54) | LPAR3LPAR2LPAR1SAT1ENPP2 | |
| SCHEMBL13401021 | 0.74 | LPAR3 (0.42) | LPAR3LPAR2LPAR1PGK1PGK2 | |
| Hexadecyl Dihydrogen Phosphate SCHEMBL9365300 | 0.73 | LPAR3 (0.72) | LPAR3LPAR2LPAR1LPAR5ENPP2 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL28098739 | 0.73 | LPAR3 (0.72) | LPAR3LPAR2LPAR1LPAR5ENPP2 | |
| SCHEMBL29098363 | 0.73 | LPAR3 (0.72) | LPAR3LPAR2LPAR1LPAR5ENPP2 | |
| SCHEMBL18501085 | 0.72 | SAT1 (0.70) | LPAR3LPAR2LPAR1SAT1ENPP2 | |
| SCHEMBL1923637 | 0.71 | LPAR3 (0.54) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL7159566 | 0.71 | LPAR3 (0.48) | LPAR3LPAR2LPAR1SAT1ENPP2 | |
| SCHEMBL1576717 | 0.71 | LPAR3 (0.64) | LPAR3LPAR2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209483-A1 | PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2023-07-12 | — | — | EP | disclosed |