SCHEMBL25836272

SCHEMBL25836272

C=C[C@@H]1O[C@H](C=C)C(C(=O)OCc2ccccc2)C1C(=O)OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 4/20 0.52
FABP5 Q01469 4/20 0.52
ALDH1A1 P00352 4/20 0.45
HCAR2 Q8TDS4 1/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 2/20 0.42
TGM2 P21980 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25836269 0.93 FABP7 (0.47) FABP7FABP5ALDH1A1HCAR2MAPK1
SCHEMBL12415464 0.79 FABP7 (0.52) FABP7FABP5ALDH1A1HCAR2MAPK1
SCHEMBL8694818 0.77 FABP7 (0.50) FABP7FABP5ALDH1A1HCAR2MAPK1
SCHEMBL8694813 0.77 FABP7 (0.50) FABP7FABP5ALDH1A1HCAR2MAPK1
SCHEMBL8694810 0.77 FABP7 (0.50) FABP7FABP5ALDH1A1HCAR2MAPK1
SCHEMBL6800695 0.76 FABP7 (0.56) FABP7FABP5ALDH1A1HCAR2MAPK1
SCHEMBL32677645 0.76 FABP7 (0.59) FABP7FABP5ALDH1A1HCAR2MAPK1
SCHEMBL8498305 0.76 FABP7 (0.59) FABP7FABP5ALDH1A1HCAR2MAPK1
SCHEMBL8498310 0.76 FABP7 (0.59) FABP7FABP5ALDH1A1HCAR2MAPK1
SCHEMBL7757018 0.75 FABP7 (0.73) FABP7FABP5ALDH1A1HCAR2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702632-B2 Ex vivo method of generating super regulatory T cells for the prevention of autoimmune disease UNIVERSITY OF MASSACHUSETTS (US) 2023-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11702632-B2 Ex vivo method of generating super regulatory T cells for the prevention of autoimmune disease ICOS, CD4, NFATC1 FABP7 3299/4885FABP5 1372/4885ALDH1A1 3692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.