Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | S1PR2 | O95136 | 6/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.56 |
| ▸ | ADH1B | P00325 | 2/20 | 0.50 |
| ▸ | ADH1C | P00326 | 2/20 | 0.50 |
| ▸ | ADH1A | P07327 | 2/20 | 0.50 |
| ▸ | ADH7 | P40394 | 2/20 | 0.50 |
| ▸ | ADH4 | P08319 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20036286 | 1.00 | EPHX1 (0.65) | EPHX1TSHRALDH1A1S1PR2S1PR1 | |
| SCHEMBL18602754 | 0.97 | — | — | |
| SCHEMBL10582942 | 0.88 | TSHR (0.71) | EPHX1TSHRALDH1A1S1PR2S1PR1 | |
| SCHEMBL10140723 | 0.88 | TSHR (0.71) | EPHX1TSHRALDH1A1S1PR2S1PR1 | |
| SCHEMBL16269880 | 0.88 | — | — | |
| SCHEMBL258536 | 0.88 | TSHR (0.71) | EPHX1TSHRALDH1A1S1PR2S1PR1 | |
| SCHEMBL24450391 | 0.83 | EPHX1 (0.83) | EPHX1TSHRALDH1A1S1PR2S1PR1 | |
| SCHEMBL22651661 | 0.83 | EPHX1 (0.83) | EPHX1TSHRALDH1A1S1PR2S1PR1 | |
| SCHEMBL21469373 | 0.83 | EPHX1 (0.83) | EPHX1TSHRALDH1A1S1PR2S1PR1 | |
| SCHEMBL14607748 | 0.83 | EPHX1 (0.83) | EPHX1TSHRALDH1A1S1PR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020333-A2 | KINASE INHIBITORS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-01-25 | — | — | WO | disclosed |
| WO-2023136213-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-20 | — | — | WO | disclosed |