Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 4/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.31 |
| ▸ | PPM1A | P35813 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25836786 | 0.85 | MEN1 (0.35) | APPMEN1KMT2AGAAMAPT | |
| SCHEMBL25876918 | 0.81 | PDK2 (0.36) | MEN1KMT2AGAAPPM1APDK2 | |
| SCHEMBL25837574 | 0.79 | GAA (0.36) | MEN1KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL26452397 | 0.79 | MEN1 (0.39) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL27165421 | 0.77 | MAPT (0.34) | APPMEN1KMT2AGAAMAPT | |
| SCHEMBL1010429 | 0.76 | ALK (0.40) | APPMEN1KMT2AGAAMAPT | |
| SCHEMBL30104208 | 0.76 | PPM1A (0.39) | APPMEN1KMT2AGAAMAPT | |
| SCHEMBL21582137 | 0.76 | PPM1A (0.39) | APPMEN1KMT2AGAAMAPT | |
| SCHEMBL26629607 | 0.76 | MEN1 (0.40) | MEN1KMT2AGAAMAPTALOX12 | |
| SCHEMBL1814871 | 0.76 | MEN1 (0.36) | MEN1KMT2AGAASMN1; SMN2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023136213-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-20 | — | — | WO | disclosed |