⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14155499 | 0.73 | — | — | |
| SCHEMBL1783853 | 0.71 | — | — | |
| SCHEMBL20931344 | 0.67 | — | — | |
| SCHEMBL16159973 | 0.66 | — | — | |
| SCHEMBL13769130 | 0.66 | — | — | |
| SCHEMBL23367917 | 0.64 | — | — | |
| SCHEMBL17461171 | 0.64 | — | — | |
| SCHEMBL20180367 | 0.63 | — | — | |
| SCHEMBL26216173 | 0.63 | — | — | |
| SCHEMBL1782011 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3722291-B1 | INDOLINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF FIBROTIC DISEASES | RESPIVERT LTD (GB) | 2023-07-19 | — | — | EP | disclosed |