Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 17/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.42 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 3/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25825183 | 0.77 | WEE1 (0.80) | WEE1EGFRPLK1CYP3A4MAP3K19 | |
| SCHEMBL25819274 | 0.77 | WEE1 (0.80) | WEE1EGFRPLK1CYP3A4MAP3K19 | |
| SCHEMBL25819065 | 0.72 | WEE1 (0.40) | WEE1EGFRPLK1CYP3A4MAP3K19 | |
| SCHEMBL25825186 | 0.72 | WEE1 (0.45) | WEE1EGFRPLK1CYP3A4MAP3K19 | |
| SCHEMBL21349561 | 0.71 | WEE1 (0.64) | WEE1EGFRPLK1CYP3A4MAP3K19 | |
| SCHEMBL25819275 | 0.70 | WEE1 (0.82) | WEE1EGFRPLK1CYP3A4MAP3K19 | |
| SCHEMBL24033621 | 0.70 | WEE1 (0.65) | WEE1EGFRPLK1CYP3A4MAP3K19 | |
| SCHEMBL25819288 | 0.69 | WEE1 (0.50) | WEE1EGFRPLK1CYP3A4MAP3K19 | |
| SCHEMBL25819292 | 0.69 | WEE1 (0.50) | WEE1EGFRPLK1CYP3A4MAP3K19 | |
| SCHEMBL25061003 | 0.68 | WEE1 (0.56) | WEE1EGFRPLK1CYP3A4MAP3K19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |