SCHEMBL25837467

SCHEMBL25837467

CONC(=O)c1sccc1C(=O)Nc1c(F)cc(-c2cccc(OC)c2)cc1F

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 19/20 0.66
NR4A2 P43354 7/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31326968 0.96 DHODH (0.70) DHODHNR4A2
SCHEMBL31326974 0.92 DHODH (0.70) DHODHNR4A2
SCHEMBL18118633 0.89 DHODH (0.81) DHODHNR4A2
SCHEMBL31026703 0.86 DHODH (0.65) DHODHNR4A2
SCHEMBL30511209 0.84 DHODH (0.77) DHODHNR4A2
SCHEMBL25839584 0.81 DHODH (0.88) DHODHNR4A2
SCHEMBL1124114 0.80 DHODH (1.00) DHODHNR4A2
SCHEMBL517805 0.78 DHODH (1.00) DHODHNR4A2
SCHEMBL1337760 0.78 DHODH (0.67) DHODHNR4A2
SCHEMBL517692 0.78 DHODH (1.00) DHODHNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023118576-A1 DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE IMMUNIC AG (DE) 2023-06-29 WO disclosed