Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25255115 | 0.99 | IRAK4 (0.35) | IRAK4RETIRAK1MAPK10 | |
| SCHEMBL26193347 | 0.86 | JMJD6 (0.37) | IRAK4RETIRAK1MAPK10 | |
| SCHEMBL25302195 | 0.85 | RET (0.35) | IRAK4RETIRAK1MAPK10 | |
| Trifluoroacetic Acid SCHEMBL30509971 | 0.81 | CCR4 (0.35) | IRAK4RET | |
| SCHEMBL25838021 | 0.80 | IRAK4 (0.40) | IRAK4IRAK1 | |
| Hydrochloric Acid SCHEMBL25299144 | 0.79 | IRAK4 (0.39) | IRAK4IRAK1 | |
| SCHEMBL25258733 | 0.79 | IRAK4 (0.35) | IRAK4IRAK1 | |
| SCHEMBL25294718 | 0.78 | JMJD6 (0.38) | RET | |
| SCHEMBL25296155 | 0.75 | BTK (0.44) | RET | |
| SCHEMBL30561773 | 0.75 | BTK (0.44) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122780-A9 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023122780-A2 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-06-29 | — | — | WO | disclosed |