SCHEMBL25837899

SCHEMBL25837899

COc1ccc(C2(c3ccc(C)cc3)C=Cc3c4c(c5ccc(C)cc5c3O2)-c2ccc(C)cc2C4)cc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
ATM Q13315 1/20 0.31
IDO1 P14902 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25837957 0.96 IDO1 (0.35) MAPTATMIDO1
SCHEMBL25877148 0.87 ALK (0.30)
SCHEMBL13988153 0.83 ALK (0.32)
SCHEMBL13880298 0.83 MEN1 (0.33) MAPTIDO1
SCHEMBL14267918 0.81 CYP1A2 (0.39) MAPTATMIDO1
SCHEMBL25877249 0.81 CHEK1 (0.31)
SCHEMBL25836099 0.81 KDM4E (0.31) MAPTATMIDO1
SCHEMBL30476316 0.80 KDM4E (0.32) MAPTATMIDO1
SCHEMBL5521348 0.79 KDM4E (0.31) MAPTATMIDO1
SCHEMBL14444800 0.78 MEN1 (0.34) MAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023136213-A1 PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES 株式会社トクヤマ 2023-07-20 WO disclosed