⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11486738 | 0.78 | CRBN (0.39) | — | |
| SCHEMBL25838000 | 0.73 | — | — | |
| SCHEMBL11128841 | 0.72 | — | — | |
| SCHEMBL25838829 | 0.68 | — | — | |
| SCHEMBL357257 | 0.68 | — | — | |
| SCHEMBL12160740 | 0.68 | — | — | |
| SCHEMBL23002185 | 0.68 | CRBN (0.41) | — | |
| SCHEMBL289406 | 0.68 | CRBN (0.41) | — | |
| SCHEMBL25837997 | 0.67 | — | — | |
| SCHEMBL20614486 | 0.66 | CREBBP (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125877-A1 | TRICYCLIC DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |