Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 17/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 2/20 | 0.46 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299558 | 0.81 | DHODH (0.77) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL31326967 | 0.81 | DHODH (0.84) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL20673315 | 0.78 | DHODH (0.78) | DHODHNR4A2TSHRNPSR1DHFR | |
| SCHEMBL25838107 | 0.78 | DHODH (0.67) | DHODHNR4A2TSHRNPSR1JMJD7 | |
| SCHEMBL25839584 | 0.77 | DHODH (0.88) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL3924998 | 0.77 | DHODH (0.86) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL20673194 | 0.76 | DHODH (0.56) | DHODHNR4A2TSHRNPSR1DHFR | |
| SCHEMBL31026705 | 0.75 | DHODH (0.52) | DHODHNR4A2TSHRNPSR1DHFR | |
| SCHEMBL31026702 | 0.75 | DHODH (0.51) | DHODHNR4A2TSHRNPSR1DHFR | |
| SCHEMBL31026709 | 0.75 | DHODH (0.51) | DHODHNR4A2TSHRNPSR1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118576-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | IMMUNIC AG (DE) | 2023-06-29 | — | — | WO | disclosed |