Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19948978 | 0.80 | USP30 (0.38) | USP30USP2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL29334072 | 0.76 | USP30 (0.38) | USP30PRMT5WDR77AAK1MEN1 | |
| SCHEMBL31043149 | 0.75 | USP30 (0.37) | USP30ALDH1A1LMNAMAPTAAK1 | |
| SCHEMBL25317580 | 0.74 | USP30 (0.35) | USP30KDM1AAAK1BUB1 | |
| SCHEMBL24364813 | 0.72 | USP30 (0.39) | USP30KDM1AAAK1BUB1 | |
| SCHEMBL25037259 | 0.72 | USP30 (0.39) | USP30KDM1AAAK1BUB1 | |
| SCHEMBL29023102 | 0.71 | USP30 (0.37) | USP30USP2SMN1; SMN2NR1H2KDM1A | |
| SCHEMBL512721 | 0.71 | USP30 (0.38) | USP30USP2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL22717694 | 0.71 | NOTUM (0.41) | USP30USP2SMN1; SMN2KDM1A | |
| SCHEMBL30697901 | 0.71 | USP30 (0.42) | USP30ALDH1A1MAPTKDM1APRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |