Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 5/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30068576 | 1.00 | MAP3K12 (0.41) | MAP3K12PIK3CGPAK1ABL1 | |
| SCHEMBL27128347 | 1.00 | MAP3K12 (0.41) | MAP3K12PIK3CGPAK1ABL1 | |
| SCHEMBL25306185 | 0.94 | MAP3K12 (0.39) | MAP3K12PIK3CGPAK1ABL1 | |
| SCHEMBL30068719 | 0.94 | MAP3K12 (0.39) | MAP3K12PIK3CGPAK1ABL1 | |
| SCHEMBL25260858 | 0.94 | MAP3K12 (0.39) | MAP3K12PIK3CGPAK1ABL1 | |
| SCHEMBL25303363 | 0.94 | MAP3K12 (0.39) | MAP3K12PIK3CGPAK1ABL1 | |
| SCHEMBL30068777 | 0.94 | MAP3K12 (0.39) | MAP3K12PIK3CGPAK1ABL1 | |
| SCHEMBL25303364 | 0.94 | MAP3K12 (0.39) | MAP3K12PIK3CGPAK1ABL1 | |
| SCHEMBL30068604 | 0.93 | MAP3K12 (0.37) | MAP3K12PIK3CGPAK1ABL1 | |
| SCHEMBL25296268 | 0.93 | MAP3K12 (0.37) | MAP3K12PIK3CGPAK1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4303216-A1 | FUSED RING SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2024-01-10 | — | — | EP | disclosed |
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |