Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.45 |
| ▸ | BRD4 | O60885 | 4/20 | 0.45 |
| ▸ | BRD2 | P25440 | 1/20 | 0.45 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | OXTR | P30559 | 8/20 | 0.43 |
| ▸ | TAF1 | P21675 | 1/20 | 0.42 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25091781 | 0.90 | CACNA1B (0.45) | BRD9BRD4BRD2BRD7KDM4E | |
| SCHEMBL25844139 | 0.85 | BRD9 (0.39) | BRD9BRD4BRD2BRD7KDM4E | |
| SCHEMBL25844193 | 0.83 | BRD4 (0.44) | BRD9BRD4KDM4EMAPK1ALDH1A1 | |
| SCHEMBL25091100 | 0.83 | BRD4 (0.46) | BRD9BRD4BRD2BRD7KDM4E | |
| SCHEMBL25844107 | 0.78 | CACNA1B (0.46) | BRD9BRD4BRD2BRD7KDM4E | |
| SCHEMBL23798059 | 0.77 | CACNA1B (0.38) | BRD9BRD4BRD2BRD7KDM4E | |
| SCHEMBL25844092 | 0.76 | BRD4 (0.44) | BRD9BRD4KDM4EMAPK1ALDH1A1 | |
| SCHEMBL23798067 | 0.76 | CACNA1B (0.35) | BRD9BRD4BRD2BRD7CYP3A4 | |
| SCHEMBL23798062 | 0.75 | CACNA1B (0.42) | BRD9BRD4KDM4EMAPK1ALDH1A1 | |
| SCHEMBL23798071 | 0.75 | BRD9 (0.53) | BRD9BRD4BRD2BRD7CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691972-B2 | Compounds for targeted degradation of BRD9 | C4 THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691972-B2 | Compounds for targeted degradation of BRD9 | BRD9, BRD1, BRWD1 | BRD9 1/4885BRD4 17/4885BRD2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.