Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK9 | Q9NPC2 | 7/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.55 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.52 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31396764 | 0.92 | KMT2A (0.59) | KCNK9KCNK3KAT6AMAPTLMNA | |
| SCHEMBL9479889 | 0.89 | MAPT (0.62) | KCNK9KAT6AMAPTLMNAMAPK1 | |
| SCHEMBL24010535 | 0.89 | BRAF (0.57) | — | |
| SCHEMBL7719125 | 0.86 | NAMPT (0.57) | KCNK9KCNK3KAT6AKMT2AMEN1 | |
| SCHEMBL24006370 | 0.85 | NAMPT (0.61) | KCNK9KCNK3KAT6AMAPTLMNA | |
| SCHEMBL24011266 | 0.85 | BRAF (0.51) | KCNK9KCNK3KAT6AKMT2AMEN1 | |
| SCHEMBL23899079 | 0.85 | NAMPT (0.65) | KCNK9KCNK3KMT2AMEN1RAB9A | |
| SCHEMBL23999957 | 0.84 | NAMPT (0.68) | KCNK9KMT2AMEN1RAB9APOLB | |
| SCHEMBL7074306 | 0.83 | NAMPT (0.57) | KAT6AKMT2AMEN1RAB9APOLB | |
| SCHEMBL13622966 | 0.83 | PTGS1 (0.55) | KCNK9KCNK3KAT6AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | KCNK9 4540/4885KCNK3 2240/4885KAT6A 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.