SCHEMBL25844414

SCHEMBL25844414

c1ccc2c(c1)-c1ccccc1C21c2ccccc2-c2cccc(-c3ccc4c(c3)Sc3cccc5cccc-4c35)c21

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.40
MAPK1 P28482 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HIF1A Q16665 1/20 0.33
PDK2 Q15119 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
NOX1 Q9Y5S8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25844317 0.97 TYMS (0.38) TYMSMAPK1ALDH1A1TSHRHSD17B10
SCHEMBL25844314 0.94 MAPK1 (0.36) TYMSMAPK1ALDH1A1TSHRHSD17B10
SCHEMBL25844412 0.88 TYMS (0.41) TYMSMAPK1ALDH1A1TSHRHSD17B10
SCHEMBL25844733 0.87 TYMS (0.38) TYMSMAPK1ALDH1A1TSHRHSD17B10
SCHEMBL25861716 0.87 TYMS (0.38) TYMSMAPK1ALDH1A1TSHRHSD17B10
SCHEMBL25853919 0.87 TYMS (0.38) TYMSMAPK1ALDH1A1TSHRHSD17B10
SCHEMBL25844411 0.87 TYMS (0.40) TYMSMAPK1ALDH1A1TSHRHSD17B10
SCHEMBL25844221 0.86 TYMS (0.37) TYMSMAPK1ALDH1A1TSHRHSD17B10
SCHEMBL25844223 0.86 TYMS (0.39) TYMSMAPK1ALDH1A1TSHRHSD17B10
SCHEMBL25845966 0.85 TYMS (0.34) TYMSMAPK1ALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 WO disclosed