Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21569008 | 1.00 | PIK3CD (0.37) | PIK3CDEGFRERBB2FGFR2CHRNB2 | |
| SCHEMBL2842621 | 0.84 | PIK3CD (0.38) | PIK3CDEGFRERBB2FGFR2 | |
| SCHEMBL14165483 | 0.84 | PIK3CD (0.38) | PIK3CDEGFRERBB2FGFR2 | |
| SCHEMBL14165482 | 0.84 | PIK3CD (0.38) | PIK3CDEGFRERBB2FGFR2 | |
| SCHEMBL2842616 | 0.84 | PIK3CD (0.38) | PIK3CDEGFRERBB2FGFR2 | |
| SCHEMBL23936998 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL15709158 | 0.82 | PIK3CD (0.37) | PIK3CDEGFRERBB2FGFR2 | |
| SCHEMBL14617834 | 0.82 | HCAR2 (0.41) | PIK3CDEGFRERBB2FGFR2 | |
| Hydrochloric Acid SCHEMBL15709160 | 0.82 | PIK3CD (0.37) | PIK3CDEGFRERBB2FGFR2 | |
| SCHEMBL2227392 | 0.82 | PIK3CD (0.37) | PIK3CDEGFRERBB2FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133543-A1 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2023-07-13 | — | — | WO | disclosed |