SCHEMBL25845255

SCHEMBL25845255

c1ccc2c(c1)-c1c(-c3cccc4c3-c3cccc5cccc(c35)S4)cccc1C21c2ccccc2-c2c1ccc1ccccc21

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.39
DNMT1 P26358 1/20 0.34
CES1 P23141 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
THRB P10828 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25853814 0.90 TYMS (0.35) TYMSDNMT1
SCHEMBL25845267 0.89 TYMS (0.45) TYMSALDH1A1HPGDHSD17B10
SCHEMBL25847100 0.89 TYMS (0.38) TYMSDNMT1CES1ALDH1A1CYP1A2
SCHEMBL25846338 0.89 DNMT1 (0.36) TYMSDNMT1CES1ALDH1A1CYP1A2
SCHEMBL25845252 0.88 TYMS (0.34) TYMS
SCHEMBL25845135 0.88 TYMS (0.37) TYMSDNMT1
SCHEMBL25845140 0.87 TYMS (0.33) TYMS
SCHEMBL25861418 0.87 TYMS (0.33) TYMS
SCHEMBL25845478 0.85 DNMT1 (0.34) TYMSDNMT1ALDH1A1
SCHEMBL25845132 0.85 TYMS (0.41) TYMSALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 WO disclosed