Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.74 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.65 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.65 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.65 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.42 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2722856 | 0.85 | MAPT (1.00) | MAPTCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL29437410 | 0.85 | MAPT (1.00) | MAPTCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL2723246 | 0.84 | MAPT (0.74) | MAPTCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL3539759 | 0.84 | MAPT (0.90) | MAPTCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL15141576 | 0.84 | MAPT (0.97) | MAPTCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL29435521 | 0.84 | MAPT (0.97) | MAPTCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL13202791 | 0.83 | MAPT (0.68) | MAPTCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL16888504 | 0.83 | MAPT (0.70) | MAPTCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL25192964 | 0.83 | POLB (0.65) | MAPTCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL30416216 | 0.83 | POLB (0.65) | MAPTCHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691972-B2 | Compounds for targeted degradation of BRD9 | C4 THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691972-B2 | Compounds for targeted degradation of BRD9 | BRD9, BRD1, BRWD1 | MAPT 1277/4885CHRNB2 4176/4885CHRNA4 4695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.