Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25847258 | 1.00 | USP2 (0.47) | USP2SMN1; SMN2TSHRALOX15HPGD | |
| SCHEMBL18423086 | 1.00 | USP2 (0.47) | USP2SMN1; SMN2TSHRALOX15HPGD | |
| Hydrochloric Acid SCHEMBL31567125 | 0.89 | USP2 (0.41) | USP2SMN1; SMN2TSHRALOX15HPGD | |
| SCHEMBL16000449 | 0.87 | USP2 (0.50) | USP2SMN1; SMN2TSHRALOX15HPGD | |
| SCHEMBL23826809 | 0.84 | USP2 (0.47) | USP2SMN1; SMN2TSHRALOX15HPGD | |
| SCHEMBL15657911 | 0.84 | USP2 (0.47) | USP2SMN1; SMN2TSHRALOX15HPGD | |
| SCHEMBL22196335 | 0.84 | USP2 (0.47) | USP2SMN1; SMN2TSHRALOX15HPGD | |
| SCHEMBL22107818 | 0.83 | USP2 (0.42) | USP2SMN1; SMN2TSHRALOX15HPGD | |
| SCHEMBL23826580 | 0.83 | USP2 (0.46) | USP2SMN1; SMN2TSHRALOX15HPGD | |
| SCHEMBL23826577 | 0.83 | USP2 (0.46) | USP2SMN1; SMN2TSHRALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250197423-A1 | RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2025-06-19 | — | — | US | disclosed |
| CN-119798279-A | RAS inhibitors | 锐新医药公司 | 2025-04-11 | — | — | CN | disclosed |
| EP-4463231-A1 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| CN-118922423-A | RAS inhibitors | 锐新医药公司 | 2024-11-08 | — | — | CN | disclosed |
| WO-2023133543-A1 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023133543-A1 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2023-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197423-A1 | RAS INHIBITORS | KRAS, NRAS, HRAS | USP2 1149/4885SMN1; SMN2 3728/4885TSHR 3332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.