Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12075527 | 0.84 | BRD4 (0.41) | BRD4KDM4EKDM4AKDM5CKDM4C | |
| SCHEMBL25820308 | 0.82 | CYP19A1 (0.35) | TGFBR1TACR3CCR1CCR8 | |
| SCHEMBL12922238 | 0.80 | CCR1 (0.46) | KDM4ETGFBR1TACR3CCR1CCR8 | |
| SCHEMBL31173176 | 0.79 | BRD4 (0.37) | BRD4KDM4EKDM4AKDM5CKDM4C | |
| SCHEMBL3510772 | 0.79 | BRD4 (0.37) | BRD4KDM4EKDM4AKDM5CKDM4C | |
| SCHEMBL17109407 | 0.77 | CCR1 (0.59) | BRD4KDM4EKDM4AKDM5CKDM4C | |
| SCHEMBL25832880 | 0.77 | CYP19A1 (0.32) | TGFBR1JAK2JAK1TYK2 | |
| SCHEMBL15981036 | 0.76 | IRAK4 (0.44) | KDM4ETGFBR1CCR1CCR8GRM5 | |
| SCHEMBL15980637 | 0.75 | CYP19A1 (0.56) | KDM4AKDM5CKDM4CKDM2AKDM3A | |
| SCHEMBL15293913 | 0.73 | KDM4E (0.44) | BRD4KDM4EKDM4AKDM5CKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | BRD4 2766/4885KDM4E 4219/4885KDM4A 4651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.