Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.53 |
| ▸ | ACHE | P22303 | 8/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8237341 | 0.86 | KDM4C (0.47) | EPHX1MMP2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10765973 | 0.84 | EPHX1 (0.55) | EPHX1ACHEMMP2ALDH1A1POLB | |
| SCHEMBL2736685 | 0.84 | EPHX1 (0.55) | EPHX1ACHEMMP2ALDH1A1POLB | |
| SCHEMBL28180263 | 0.83 | EPHX1 (0.50) | EPHX1ACHEMMP2ALDH1A1POLB | |
| SCHEMBL8394868 | 0.80 | EPHX1 (0.52) | EPHX1ACHEMMP2ALDH1A1POLB | |
| SCHEMBL5021617 | 0.80 | EPHX1 (0.52) | EPHX1ACHEMMP2ALDH1A1POLB | |
| SCHEMBL14399362 | 0.80 | EPHX1 (0.62) | EPHX1ACHEMMP2ALDH1A1POLB | |
| SCHEMBL22351756 | 0.80 | EPHX1 (0.52) | EPHX1ACHEMMP2ALDH1A1POLB | |
| SCHEMBL10251931 | 0.80 | EPHX1 (0.62) | EPHX1ACHEMMP2ALDH1A1POLB | |
| SCHEMBL9499965 | 0.80 | PAOX (0.47) | EPHX1ALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |