Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 4/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 3/20 | 0.35 |
| ▸ | DLK1 | P80370 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25839912 | 1.00 | MAP3K12 (0.36) | MAP3K12PAK1DLK1PIK3CGAAK1 | |
| SCHEMBL30491292 | 1.00 | MAP3K12 (0.36) | MAP3K12PAK1DLK1PIK3CGAAK1 | |
| SCHEMBL25856017 | 0.93 | MAP3K12 (0.35) | MAP3K12PAK1DLK1PIK3CGAAK1 | |
| SCHEMBL31150760 | 0.92 | MAP3K12 (0.37) | MAP3K12PAK1PIK3CG | |
| SCHEMBL25848044 | 0.92 | MAP3K12 (0.37) | MAP3K12PAK1PIK3CG | |
| SCHEMBL25296626 | 0.91 | MAP3K12 (0.40) | MAP3K12DLK1PIK3CG | |
| SCHEMBL25296625 | 0.91 | MAP3K12 (0.40) | MAP3K12DLK1PIK3CG | |
| SCHEMBL30491249 | 0.91 | MAP3K12 (0.40) | MAP3K12DLK1PIK3CG | |
| SCHEMBL30491236 | 0.91 | PAK1 (0.39) | MAP3K12PAK1PIK3CGAAK1PKN1 | |
| SCHEMBL25848577 | 0.91 | PAK1 (0.39) | MAP3K12PAK1PIK3CGAAK1PKN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |