Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13804186 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2USP2RECQLHSD17B10NPC1 | |
| SCHEMBL15116754 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2USP2RECQLHSD17B10NPC1 | |
| SCHEMBL185522 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2USP2RECQLHSD17B10NPC1 | |
| SCHEMBL186174 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2USP2RECQLHSD17B10NPC1 | |
| SCHEMBL154453 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2USP2RECQLHSD17B10NPC1 | |
| SCHEMBL25853657 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2USP2RECQLHSD17B10NPC1 | |
| SCHEMBL3511572 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2USP2RECQLHSD17B10NPC1 | |
| SCHEMBL16359137 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2USP2RECQLHSD17B10NPC1 | |
| SCHEMBL16604806 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2USP2RECQLHSD17B10NPC1 | |
| SCHEMBL16604796 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2USP2RECQLHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |