SCHEMBL25849771

SCHEMBL25849771

CC(C)c1ccc2c(c1)C(C)(C)c1cc(C=C3C(=O)c4cc5ccccc5cc4C3=O)ccc1N2C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.41
CSNK2B P67870 1/20 0.41
CSNK2A1 P68400 1/20 0.41
CSNK2A3 Q8NEV1 1/20 0.41
EGFR P00533 1/20 0.37
ERBB2 P04626 1/20 0.37
IGF1R P08069 1/20 0.37
PDGFRB P09619 1/20 0.37
GLB1 P16278 1/20 0.37
CTRC Q99895 1/20 0.37
NR1H3 Q13133 1/20 0.37
LCK P06239 2/20 0.36
MAPT P10636 7/20 0.36
KMT2A Q03164 6/20 0.36
ALDH1A1 P00352 4/20 0.36
USP2 O75604 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
MEN1 O00255 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22177115 0.91 LCK (0.40) ERBB2LCKMAPTKMT2AALDH1A1
SCHEMBL25849769 0.89 CSNK2A2 (0.39) CSNK2A2CSNK2BCSNK2A1CSNK2A3EGFR
SCHEMBL22177580 0.88 MAPT (0.42) ERBB2LCKMAPTKMT2AALDH1A1
SCHEMBL25849767 0.86 MAPT (0.42) CSNK2A2CSNK2BCSNK2A1CSNK2A3LCK
SCHEMBL22177619 0.86 MAPT (0.41) ERBB2LCKMAPTKMT2AALDH1A1
SCHEMBL25849759 0.84 LCK (0.33) CSNK2A2CSNK2BCSNK2A1CSNK2A3EGFR
SCHEMBL22177616 0.84 BCL2 (0.36) LCKMAPTKMT2AALDH1A1USP2
SCHEMBL15118355 0.84 CSNK2A2 (0.35) CSNK2A2CSNK2BCSNK2A1CSNK2A3EGFR
SCHEMBL25849768 0.84 NR1H3 (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3NR1H3
SCHEMBL22177161 0.83 NR1H3 (0.37) ERBB2NR1H3LCKMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed