SCHEMBL25850064

SCHEMBL25850064

CC(C)(C)CC(=O)NCCc1ccc(O)c(O)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.65
HSD17B10 Q99714 4/20 0.65
HPGD P15428 4/20 0.65
KDM4E B2RXH2 4/20 0.65
ALDH1A1 P00352 4/20 0.65
HIF1A Q16665 3/20 0.65
LMNA P02545 3/20 0.65
BLM P54132 3/20 0.65
PTGS1 P23219 1/20 0.65
TRPV1 Q8NER1 3/20 0.60
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
ERCC1 P07992 1/20 0.57
ERCC4 Q92889 1/20 0.57
GAA P10253 2/20 0.56
ALPL P05186 1/20 0.56
ALOX12 P18054 2/20 0.55
TP53 P04637 2/20 0.54
CYP1A2 P05177 2/20 0.54
ALOX15 P16050 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28976216 0.94 MEN1 (0.61) MAPTHSD17B10HPGDKDM4EALDH1A1
SCHEMBL18557027 0.88 MAPT (0.61) MAPTHSD17B10HPGDKDM4EALDH1A1
SCHEMBL21377593 0.85 MAPT (0.65) MAPTHSD17B10HPGDKDM4EALDH1A1
SCHEMBL17205984 0.83 MAPT (0.71) MAPTHSD17B10HPGDKDM4EALDH1A1
SCHEMBL12412212 0.83 ESRRG (0.64) MAPTHPGDKDM4EGAACYP1A2
SCHEMBL109158 0.82 MAPT (0.73) MAPTHSD17B10HPGDKDM4EALDH1A1
SCHEMBL11734210 0.81 MAPT (0.69) MAPTHSD17B10HPGDKDM4EALDH1A1
SCHEMBL2266963 0.81 MAPT (0.68) MAPTHSD17B10HPGDKDM4EALDH1A1
SCHEMBL107219 0.81 MAPT (0.71) MAPTHSD17B10HPGDKDM4EALDH1A1
SCHEMBL109104 0.81 MAPT (0.68) MAPTHSD17B10HPGDKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226519-A1 Metal Chelating Functional Graphene Materials CARNEGIE MELLON UNIVERSITY 2023-07-20 US disclosed
US-20230226519-A1 Metal Chelating Functional Graphene Materials CARNEGIE MELLON UNIVERSITY 2023-07-20 US disclosed