SCHEMBL25850196

SCHEMBL25850196

CC(C)C(=O)[C@H](CCCCNC(=O)CC[C@H](NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O)NC(=O)CC[C@H](NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.70
▸ CCKAR P32238 8/20 0.45
▸ CCKBR P32239 8/20 0.45
▸ FOLH1 Q04609 2/20 0.44
▸ NOD1 Q9Y239 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24494710 0.94 GLP1R (0.68) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL24494709 0.94 GLP1R (0.67) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL25912500 0.90 GLP1R (0.72) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL25912496 0.90 GLP1R (0.72) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL15579830 0.90 GLP1R (0.72) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL12118771 0.90 GLP1R (0.72) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL22648333 0.90 GLP1R (0.73) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL17682400 0.90 GLP1R (0.74) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL13951978 0.89 GLP1R (0.70) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL24173321 0.89 GLP1R (0.70) GLP1RCCKARCCKBRFOLH1NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11840560-B2 Prodrugs and uses thereof NOVO NORDISK A/S (DK) 2023-12-12 — — US disclosed
US-20230227521-A1 PRODRUGS AND USES THEREOF NOVO NORDISK A/S (DK) 2023-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11840560-B2 Prodrugs and uses thereof GIPR, GLP1R, GRPR GLP1R 2/4885CCKAR 21/4885CCKBR 20/4885
US-20230227521-A1 PRODRUGS AND USES THEREOF GIPR, GLP1R, GRPR GLP1R 2/4885CCKAR 21/4885CCKBR 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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