Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 16/20 | 0.71 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.33 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.33 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25853547 | 0.83 | STING1 (0.58) | STING1 | |
| SCHEMBL23630804 | 0.83 | STING1 (1.00) | STING1 | |
| SCHEMBL23630803 | 0.75 | STING1 (1.00) | STING1ALDH1A1HPGD | |
| SCHEMBL23112028 | 0.73 | STING1 (0.79) | STING1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL23635912 | 0.72 | STING1 (0.82) | STING1MCL1SENP5SENP2SENP1 | |
| SCHEMBL23630772 | 0.71 | STING1 (0.71) | STING1POLBL3MBTL1 | |
| SCHEMBL25853307 | 0.71 | STING1 (0.59) | STING1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL25853644 | 0.71 | STING1 (0.50) | STING1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL25853493 | 0.70 | STING1 (0.61) | STING1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL23111987 | 0.69 | STING1 (0.78) | STING1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227423-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227423-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | STING1, CGAS, IRF3 | STING1 1/4885MCL1 1773/4885SENP5 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.